Importantly, the US CDC guidelines also states that patients keen to start on HIV PrEP after their HIV PEP can do so immediately following the completion of 28-day PEP, and provided the patient has a negative 4th generation HIV Antigen/Antibody test: Because no evidence exists that prophylactic antiretroviral use delays seroconversion and PEP is highly effective when taken as prescribed, a gap is unnecessary between ending PEP and beginning PrEP The Joint WHO/ILO guidelines on post-exposure prophylaxis (PEP) to prevent HIV infection recommends HIV testing at baseline, immediately after completing PEP (i.e. 4 to 6 weeks post exposure) and again '3 - 6 months post exposure' Successfully completing PEP is a very good predictor of being HIV negative. Successful completion means being treated on a regular schedule that has been set up by a doctor, and sticking to that schedule for the entire 28 days. As for your test results, however, they are only considered conclusive 12 weeks after completing PEP On post-exp prop (PEP). on day 8 after exposure headache, sore throat. dr ordered HIV antibody/p24 test. Negative. Was this test valuable taken at day 10 after exposure if these were indeed acute HIV symptoms I did ask the GUM clinic about the impact of PEP on test results and seroconversion but they were pretty non-commital. Their line has always been that the important tests are at 3 months and 6 months, that any earlier test might give a false negative
Clinically, when one has tested negative at week 4 for HIV after going through the new PEP regime, it is deemed conclusive. Besides, a condom was used, technically speaking, PEP was unwarranted given the inherent low risk. Relax, you are fine. Should you wish to do a retest at day 90, please do so 14, 28). Serum should be tested for rabies neutralizing antibody 1-2 weeks following completion of series. Consult your local health department if deviations from the PEP schedule occur. If the biting animal is captured and tests negative for rabies after PEP has begun, PEP may be discontinued. References i tested negative at 7 weeks post exposure, that's 3 weeks post pep, but i got already the fever that day i got a swollen lymph in the neck.. very small.. i thought it was a pimple first. it went away in less than an hour, after fever broke, because of a paracetamol i took im thinking an PCR test, my doctor didn't recommended because he said, it wouldn't be conclusive, that i should wait for. i was exposed on 27th dec ,started pep on 28th dec after 28 hours.i finished pep on 26th Jan.then that is when i started getting the sympotoms,it is 5 weeks after PEP and i still have joint pains. and once a while i get a headache ,my nodes have been swollen every since.my skin is peel and dry
As a result, people taking HIV treatment who use rapid, point-of-care tests or self-tests (especially those which are based on oral fluid samples) may receive false negative results. This is a rare phenomenon in people who began HIV treatment several months or years after infection Tested Negative immediately after PEP Completion Hello Doctor, I had an exposure where condom broke while doing anal intercourse (quite brief, may be 3 thrusts unprotected) I was put on PEP after 48 hours (2 days). One day after 28 days of PEP completion, I took 4th generation test which come back Negative (30 days post exposure, 1 day post PEP) It's probably possible to test antibody positive after a PEP course. This could happen if infection actually occurred and PEP fails to control the virus well. Tested Negative immediately after PEP Completion. benzthai. 28 days of PEP completion, I took 4th generation test which Negative (28 days post exposure) 1. However, I would like to.
Testing immediately after PEP completion can be useful if the PEP was not successful at preventing the HIV from establishing an infection. However, a test conducted immediately after PEP completion cannot be considered completely conclusive because the drugs that PEP consists of may have suppressed the replication of the virus Rapid HIV tests are generally very sensitive and specific and can be used to determine whether to offer PEP. A positive rapid HIV test should be preliminarily considered a true positive for the purposes of initial PEP decision-making. A negative rapid test should be considered a true negative Of these 11 diagnoses, 6 occurred at intake when patients sought PEP, and 5 occurred within 12 months of using PEP; none of these 5 diagnoses were PEP failures, as all had tested negative after using PEP PEP, or post-exposure prophylaxis, is a short course of HIV medicines taken very soon after a possible exposure to HIV to prevent the virus from taking hold in your body. You must start it within 72 hours (3 days) after a possible exposure to HIV, or it won't work. Every hour counts! PEP should be used only in emergency situations Nonoccupational post-exposure prophylaxis (nPEP) can be used to clarify exposure type. Exposure to HIV is a medical emergency, because HIV establishes infection very quickly, often within 24 to 36 hours after exposure. 1, 2 3. Health care providers should evaluate persons rapidly for PEP when care is sought ≤72 hours after a potential exposure
Can I take a 4th generation hiv duo test one day after completion of pep ie 29th day after exposure and what is its accuracy? 2 doctor answers • 4 doctors weighed in 90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more I wanted to follow up about my recent Negative Exam results.I was reading online some articles about testing after PEP and I got some anxiety. some say that PEP can delay seroconversion so testing soon after PEP completion may not be accurate. But some other articles say that PEP does not affect test results and that there is no proof of PEP. PEP is the use of antiretroviral medication to prevent HIV infection in an HIV-negative person who has had a specific high-risk exposure to HIV. PEP may be indicated with transition of the patient to PrEP after completion of 28 days of PEP medication. PEP should not be started. However, if rapid HIV baseline test is not available, there.
A negative result should be followed up by repeating the HIV test after completion of PEP, at 4 to 6 weeks, 3 months, and 6 months according to the Centers for Disease Control and Prevention guidelines, Centers for Disease Control and Prevention; US Department of Health and Human Services. Updated guidelines for antiretroviral postexposure. Thanks Paul. Personally, I am a bit hesitant in using viral load tests for patients finishing PEP (despite them being extremely keen on it!) because of the theoretical risk of viral suppression sustained after ART. My advice to them is to rely on antibody test 4-6 weeks after PEP for conclusive results First of all initiation of PEP in 72 hours after potential exposure to abort infection and initiation of ART during acute phase to treat infection are two totally different things! PEP and delayed seroconversion is more of a legend than a reality!..
awaiting results of the repeat HIV test. • To transition from PEP to PrEP, check an HIV 4th gen Ag/Ab test while on week 4 of PEP and prescribe PrEP so the patient can start PrEP the day after PEP is completed. Confirm that the HIV testing done during week 4 of PEP is negative. PrEP Guide / pg 2 of Certainly any negative or undetectable HIV test is encouraging; however, we have no specific statistics on how reliable a quantitative HIV RNA PCR is 3.5 weeks after completing a course of PEP
One additional patient tested negative at his baseline visit and at 11 days following the completion of PEP, but tested HIV positive at five months — indicating another potential PEP failure. The fourth case was considered unlikely to be a PEP failure, as they tested HIV negative as late as one year after receiving PEP (15) At this point in time, we simply do not know if going on Post-Exposure Prophylaxis (PEP) after an occupational exposure to HIV, will affect the HIV antibody window period or not Baseline HIV testing was negative. On day 21 of PEP, the patient contacted the physician to inquire about pre-exposure prophylaxis (PrEP), stating that she heard about PrEP from a colleague. The physician called the CCC to ask whether and how to transition this patient from PEP to PrEP
I have no symptoms. Isolate for at least 10 days after first positive test.: I have symptoms of COVID-19. Isolate for at least 10 days after symptom onset and until fever free for at least 24 hours.: I am a close contact.: Quarantine for at least 10 full days from last potential exposure; self-monitor daily for symptoms through Day 14 Post‐exposure prophylaxis (PEP) is very effective at preventing transmission of HIV in cases of obtaining the supply of PEP drugs to complete the 28‐day regimen. negative baseline test documents that the worker was HIV negative at the time of the. Individuals who report a high-risk sexual exposure are candidates for PrEP, immediately if PEP is not indicated or upon completion of PEP once a negative HIV status is confirmed. Provide a referral for PrEP care if it is not available on site. Sexual Assault Exposure
On the 25th July, 16 days after I used condom again and it got broken unknown to me until after ejaculation then I realized. I went for a rapid card test on the 28th July, I tested negative 19 days after the first exposure and 3 days after the second exposure. I was placed on PEP from that date 9pm till date, to complete PEP on the 26th August Therefore, based on dr tan and partners yrs of experience, a patient who has tested negative at day 28 after completing pep is highly indicative, and they have never seen anyone contract hiv at day 90 of testing with a 3rd gen test except for one case where the patient continuously engaged in high risk activities while under pep negative HIV test result should be documented before initiating PrEP and every 3 months there-after. The patient should report immediately to clinic if they develop symptoms compatible with acute HIV infection (fever with sore throat, rash, or headache) Hello sir I had paid sex and condom broke from top during sex I realised it after activity completion I immediately cleaned my penis . I was scared so I started PEP within 24hrs I am taking 5 tablet
Discontinue PEP if the source patient's HIV antibody test result is negative. Patients should be educated that it takes approximately 2 years to transition. However, increasing the dosage of hormones will hasten the transitioning proces No test can detect an HIV infection immediately after contraction. After contracting HIV, the immune system begins to develop antibodies to attack the virus. This process is called seroconversion However, before most of the population is inoculated, and even then, you still need to exercise caution. You still can test positive for COVID-19 after getting the vaccine, but there are a lot of. euthanized immediately and tested. or mucous membrane exposure did not occur, or the bat tested negative for rabies, postexposure prophylaxis is not necessary. credit hour to the participant upon successful completion. The rabies PEP CE course is accessible at A positive rapid test result requires a confirmatory HIV 1/2 Ab differentiation immunoassay. If the rapid HIV test is not available on a timely basis, PEP treatment should be started knowing that it can be stopped if the test yields a negative result
. If the test is negative, you will be counseled on how to reduce your risk of HIV moving forward Therefore, it is important to get tested for the hepatitis B 3 panel blood test (HBsAg, HBcAb, HBsAb) at least 9 weeks after the exposure to determine if you have been infected. If you remain uninfected after that time period and are HBsAb negative, the completion of the hepatitis B vaccine series is strongly recommended the person has a negative PCR test (not antigen test). Asymptomatic with positive antigen test Isolate and obtain confirmatory PCR test within 48 hours. If negative and continues to be asymptomatic, can resume athletics. If positive continue isolation for 10 days from date of first positive test, or longer as per CDC guidelines during confinement, it should be immediately evaluated by a veterinarian and euthanized for rabies testing, based on the veterinarian's assessment. The exposed individual can start PEP prior to completion of rabies testing in high risk situations or when testing is delayed. PEP can be discontinued if test results are negative for rabies
able to start HIV treatment as soon after infection as possible. A negative test result at 6 weeks does not completely rule out the possibility of becoming infected with HIV as you will still be in the window period. The second test at 12 weeks covers the window period. If this test is negative, your PEP follow-up is complete. If you have had. How Soon After Exposure to HIV Can an HIV Test Detect If You Are Infected? No HIV test can detect HIV immediately after infection. If you think you've been exposed to HIV, in the last 72 hours, talk to your health care provider about post-exposure prophylaxis (PEP), right away. The time between when a person gets HIV and when a test can accurately detect it is called the window period -Sexual partner HIV & HCV negative • 10 weeks earlier: acute mononucleosis-like syndrome • 3 weeks before onset of illness (13 weeks before positive HIV test) -Punched a man in the teeth while making an arrest -Noticed 2 wound on his hand, covered with blood, but did not wash it immediately after the inciden MERS-CoV rRT-PCR was performed on samples obtained from HCWs in the PEP group immediately after and seven days after completion of the PEP protocol. All test results were negative. Serum samples collected at six and 12 weeks after unprotected high-risk exposure were negative for MERS-CoV antibody Unfortunately, PEP isn't always available and healthcare providers may only give it to you if they feel you're at a high risk of HIV. If you take PEP you'll need to test before and after to ensure it has worked. If the time to take PEP has passed, then most modern HIV tests are now able to detect HIV from around four weeks after exposure
Take Emergency PEP After Exposure to HIV. PEP − Post-Exposure Prophylaxis − is an emergency medication for people who are HIV-negative and may have been exposed to HIV. If you think you were exposed to HIV, call the NYC PEP hotline at (844) 3-PEPNYC (844-373-7692) or go immediately to a clinic or emergency room and ask for PEP This can result in false negatives on an antibody test if the proper waiting period is not observed after completion of medications. The standard antibody window period begins after the last day of PEP treatment. Doctors will advise patients who received PEP to get an antibody test at 6 months post-exposure as well as the standard 3 month test This story was updated Oct. 5 at 12:06 p.m. Oct. 3, 2020 -- White House press secretary Kayleigh McEnany's positive COVID-19 test raises more concerns about relying on tests to rule out the disease
1. I have a possible exposure 4 months back. I have got 4th gen DUO test after 4 months which checks for HIV1/2 antibodies and HIV1 antigen which turned out to be negative . 2. This test rules out every case of seronegativity mentioned in this page except this section Unknown - Sero-Negative HIV Infections in case of HIV 2 . 3 Despite knowing the recommendations, especially after PEP, I was preoccupied enough with the idea of transmission that I recently got a DNA PCR- at about 7-8 weeks post exposure; 3-4 wks after completion of PEP.It was negative. Based on the literature and your personal opinion, what do you think the risk of me seroconverting is at 3 mo, 6 mo, or year These five participants reportedly completed the prescribed 28 days of medication, with four of the five having documented negative HIV test results from routine follow-up 4 months after completing PEP; one participant with no documented follow-up testing was diagnosed during routine testing about 1 year after taking PEP, and he reported a. immediately after use. • Do not recap needles. • Use safety devices if available. All HCP should receive the HBV vaccine series and consider testing for HBV response one month after completion of the series. PEP Step 1: Treat Exposure Site Use soap and water to wash areas exposed to potentiall
PEP (post-exposure prophylaxis) Who should consider taking PEP? If you are HIV-negative and you think you may have been recently exposed to HIV, contact your health care provider immediately or go to an emergency room right away. You may be prescribed PEP if you are HIV negative or don't know your HIV status, and in the last 72 hours yo • If SP is HBV negative, no follow-up testing is clinically indicated for the EP. • Follow-up testing is only necessary for exposed persons who do not have hepatitis B immunity (i.e., do not have baseline positive HBsAb after complete vaccine series or do not have knowledge that they responded to the vaccine series) If you get a negative antibody/antigen test result during the window period, you should get another test 3 months after your possible exposure. Nucleic acid tests (NAT) look for HIV in the blood. The NAT can give either a positive/negative result or the actual amount of virus present in the blood (known as a viral load test ) There's no HIV test that can accurately detect HIV in the body immediately after exposure. There's a timeframe known as the window period before you can be tested for HIV and receive. The sooner you start Post-Exposure Prophylaxis (PEP) after a possible HIV exposure, the better. While taking Post-Exposure Prophylaxis (PEP), it's important to keep using other HIV prevention methods, such as using condoms the right way every time you have sex and using only new, sterile needles and works when injecting drugs
When you finish taking your 28 days of medication, you will get another HIV test. Many people who test HIV-negative after taking PEP are asked if they want to start taking PrEP. If you think you might have future HIV scares that require PEP, it's a good idea to consider starting PrEP • If patient reports ongoing risk behaviors (i.e., injection drug use) and is HIV-negative, counsel on the option of PrEP; transition to PrEP can occur immediately after completion of nPEP (if nPEP is not prescribed, PrEP initiation can occur once the patient is confirmed to be HIV negative and has adequate renal function A 28-day course of HIV non-occupational post-exposure prophylaxis (nPEP) should be considered for all HIV-negative persons who seek care ≤72 hours after a sexual exposure to blood, genital secretions, or other potentially infectious body fluids of a person who is living with HIV (PLWH) or is of unknown HIV status, if that exposure represents. Post-Exposure Prophylaxis (PEP) is a medication regimen that you can take if you believe you have just been exposed to HIV. If you take PEP as directed, it can prevent HIV from infecting your body. PEP must be taken within 72 hours of exposure, but should be taken as soon as possible to maximize the chance it will work
Dispose of used sharps in puncture-proof receptacles immediately after use. Do not recap needles. Use safety devices if available. All HCP should be vaccinated with the hepatitis B vaccine series and should undergo testing for HBsAb response after completion of the series to document adequate protection PEP immediately after acute high-risk exposures and for those who engage in recurrent high-risk behaviours are promising bio-behavioural approaches to decreasing HIV transmission. There is growing evidence supporting the benefits of pre-exposure prophylaxis in high-risk individuals PEP and medication after rape Combination therapy of Zidovudine (AZT) and Lamivudine (3TC) for 28 days Started within 72 hours of the rape/exposure HIV test done immediately or within 3 days of starting PEP Dispensing of drugs depends on when HIV test done, resources for return visits 3 day start-up pack, 7, 14 & 28 day pack 1. Chlamydia: When to Test for Chlamydia: Chlamydia testing can take place within 1-5 days from exposure, but is most accurate after 5. Retesting: If negative, retesting needs to occur after 5 days have elapsed. If it comes back positive, you should retest 2-4 weeks later to ensure the Chlamydia trachomatis bacteria is clear from your system.; How Often: The CDC recommends men and women at. After a person contracts HIV, seroconversion is the period during which the body starts producing detectable levels of HIV antibodies. Before this period, HIV tests usually give negative results
PEP may be indicated if a potential bat exposure cannot be ruled out. If the person can be reasonably certain a bite, scratch, or mucous membrane exposure did not occur, or the bat tested negative for rabies, post-exposure prophylaxis is not necessary. Online Rabies PEP Continuing Education Course for Provider On March 11, Kidero tested negative for the virus after undergoing tests following Raila Odinga's hospitalisation. Raila tested positive after a tour in the Coast region, which Kidero had accompanied him. Because of Raila's status, the former governor decided to take the tests whose results came out negative Guidance on risk assessment, PEP, and testing after exposure is available through PEPline, the National Clinicians' Post-Exposure Prophylaxis Hotline. The PEPline service is staffed by trained HIV PEP experts and is available 24 hours a day, 7 days a week, free of charge at 888-448-4911
A newly identified RNA-binding protein is dephosphorylated after immunity-induced Pep1 perception in Arabidopsis and maize. This modification induces alternative splicing-mediated production of a. Post-Exposure Prophylaxis (nPEP) and Occupational PEP (oPEP) February 2015 unless they have not responded after a second complete vaccination series (after two 3-dose series) • Negative HIV antibody test immediately (i.e., within one week) before starting PrEP medication. Anonymous tests, patient-self reported test results or ora As part of a multipronged initiative to restore residential learning, expand research activities, and return to campus life, Boston University has instituted our own COVID-19 screening, testing, and contact tracing program for all members of the BU community arriving on campus—undergraduate students, graduate and professional students, faculty, and staff 11. Be transported to the approved property after completion of the testing, Immigration and Customs clearance processes. 12. Be quarantined at the approved location for 4 complete days. 13. Travellers will test on Day 4 and await results before release; a. If positive, the traveller will be isolated and care provided as needed for a minimum of.
Rabies. PEP is commonly and very effectively used to prevent the onset of rabies after a bite by a suspected-rabid animal, since diagnostic tools are not available to detect rabies infection prior to the onset of the nearly always-fatal disease. The treatment consists of a series of injections of rabies vaccine and immunoglobulin. Rabies vaccine is given to both humans and animals who have. Further, some people can test positive, then negative, then positive again. Hospitals often test people with symptoms twice to try to be more certain about the finding, NPR reports Considering the speed with which the virus multiplies and the results of animal experiments it is recommended to start PEP within 6 hours of suspected exposure. Do not wait for laboratory results , start PEP at once. In most cases it is possible to stop PEP immediately after the results prove negative and thus avoid potential adverse events There is no single correct answer to this question. One recommended strategy is to get tested 2-4 weeks, 3 months, and 6 months after a risky exposure. Using a sensitive antigen/antibody HIV test, of those who are infected, most will test positive at 1 month; almost all will test positive at 3 months; and the rest will test positive at 6 months
. If both test results are negative, access to campus will be activated on day five. Students who test negative will be allowed to move into their on-campus housing and begin normal activities. After completing arrival testing, all students will be entered into Cornell's surveillance testing program 60061-7 (2021-01) Accula SARS-CoV-2 IFU 3 process positive and negative controls, enzymes, OscAR™ reagents, and a detection strip necessary for the full completion of the assay
A complete course of post-exposure prophylaxis HIV treatment involves taking PEP for about a month. PEP is considered effective, but not 100%. For this reason, you should continue to use other forms of HIV prevention and consult an experienced primary care provider for HIV testing and prevention strategies A stress test is generally safe, and complications are rare. But, as with any medical procedure, there is a risk of complications, including: Low blood pressure. Blood pressure may drop during or immediately after exercise, possibly causing you to feel dizzy or faint. The problem should go away after you stop exercising Please Note: The test will be held on 10th January 2021. The test will be conducted in OFFLINE MODE (ONLY) at our Delhi and Bengaluru Centres. After you are selected in the scholarship test, you can avail the PEP programme either in Offline Mode or Online Mode. Interested aspirants, kindly fill the below form After first vaccination series- HBIG (0.06 mL/kg IM) x 1 and revaccinate4 Revaccinate4 After second vaccination series- HBIG (0.06 mL/kg IM) x 2 (at time of exposure and 1 month after exposure) No PEP Vaccination Completed (HBsAb response unknown) Test exposed person for HBsAb. If HBsAb ≥ 10 mIU/mL, no PEP necessary. No PEP Test exposed. Approved to significantly reduce the risk of sexually acquired HIV-1 in individuals at risk 1,2. TRUVADA FOR PrEP is one tablet taken once daily. 1 HIV-1-negative status must be confirmed immediately prior to initiating TRUVADA FOR PrEP and at least every 3 months thereafter
Post-exposure prophylaxis involves taking anti-HIV medication immediately after you may have been exposed to HIV to minimize the chances of turning HIV positive. The medications keep HIV from duplicating itself and spreading to the rest of the body. Upon successful completion of the PEP treatment, more than 90% of HIV risk is reduced Isolation requirements. According to CDC isolation guidance, individuals who tested positive and experience symptoms can be with others after at least 10 days since their symptoms first appeared, after at least 24 hours with no fever without fever-reducing medication, and after symptoms have improved.Individuals who tested positive but did not experience symptoms can be with others after 10. 8. Patients presenting for rabies PEP even months after having been bitten should be treated as if the contact had recently occurred 9. PEP should be administered even if the suspect animal is not available for testing or observation. However, vaccine and immunoglobulin administration may be discontinued if the anima
All other team members have tested negative for COVID-19. Local media reported that spinner Chakaravarthy had left the bio-bubble for a shoulder scan after which the positive cases were reported Recent evidence shows PEP uptake has been insufficient: only 57% of the people who initiated PEP have completed the full course and rates were even lower at 40% for victims of sexual assault. Why guidelines are needed. For many people that are accidentally exposed to HIV, PEP provides a single opportunity to prevent HIV after exposure . is defined as any percutaneous injury, penetration of skin resulting from a needle or other sharp object, which has been in contact with blood, tissue, or other body fluids prior to the exposure 1).The United States Centers for Disease Control and Prevention (CDC) estimates that about 600,000-1,000,000 needle stick injuries occur annually 2)
The CDC recommends getting tested three to five days after returning from a holiday trip and to stay home for seven full days, even if you test negative . Recommended Post-Exposure Prophylaxis for Hepatitis B Virus. Screening-test-negative CDC does not recommend getting tested again in the three months after a positive viral test, as long as you do not have symptoms of COVID-19. If you have had a positive viral test in the past three (3) months, and you have met the criteria to end isolation, you may travel instead with documentation of your positive viral test results and a letter from your healthcare provider or a public. Follow these steps to test your battery: Before you begin testing, make sure the ignition key and all of your vehicle's lights are off. Connect the red or positive voltmeter test lead to your battery's positive terminal. Then, connect the black or negative voltmeter test lead to your battery's negative terminal. Compare your reading to this chart
If your test results are negative, you can return to your normal daily routine if you do not have symptoms. Keep in mind you should remain at home if you are still sick. While you may have tested negative for COVID-19, it is possible you have another illness that could spread to others and tested for rabies immediately. The decision about rabies PEP can usually await the testing result. Please keep in mind that rabies testing requires a one-day turnaround time by the IDPH and the Illinois Department of Agriculture (IDA) laboratories; emer-gency rabies testing is available after consultation with public health authorities STEP C. Determine PEP recommendations using table below All students with exposure code 1, 2, or 3 who desire PEP are recommended to take the expanded regimen PEP (3 drugs in two tablets). Exposure code (EC) Status Code (SC) for HIV source PEP (all courses are for 28 days) 1, 2, 3 1 or 2 Truvada and Raltegravir (this is the generic name fo . a. If the source is HIV negative, then discontinue PEP, but follow laboratory monitoring schedule as below on site and at Student Health on return b. If the source is HIV positive, you will need to continue PEP for 28 days 5) If you need to continue PEP for 28 days, you have two options: a Then other factors might come into play, if those individuals had no other exposures to the confirmed HIV pos individual during the last exposure and test, if they have been abusers of drugs, if they are immunosup. therapy, if they had PEP, if they have a co-infection etc etc. 12 weeks should be enough, its ok to test in the window period 6 wks.